Autonomic/POTSIn perspective.
The key COVID-19 findings in autonomic/pots, distilled into a clear, readable brief. The evidence is here whenever you want to go deeper.
Study findings updated
AI-assisted evidence summary. For general information. These findings are not individual medical advice or a clinician endorsement.
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The newest findings added to this collection.
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Browse the 25 original sourcesThe complete bibliography behind this monitor.
- [1]
Blitshteyn S, Whitelaw S. Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients. Immunologic Research. 2021;69(2):205-211.
Open original source in a new tab - [2]
Dani M, Dirksen A, Taraborrelli P, et al. Autonomic dysfunction in 'long COVID': rationale, physiology and management strategies. Clinical Medicine. 2021;21(1):e63-e67.
Open original source in a new tab - [3]
Raj SR, Arnold AC, Barboi A, et al. Long-COVID postural tachycardia syndrome: an American Autonomic Society statement. Clinical Autonomic Research. 2021;31(3):365-368.
Open original source in a new tab - [4]
Novak P. Post COVID-19 syndrome associated with orthostatic cerebral hypoperfusion syndrome, small fiber neuropathy and benefit of immunotherapy: a case report. eNeurologicalSci. 2020;21:100276.
Open original source in a new tab - [5]
Fedorowski A, Sutton R. Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome. Nature Reviews Cardiology. 2023;20(5):281-282.
Open original source in a new tab - [6]
Shouman K, Vanichkachorn G, Cheshire WP, et al. Autonomic dysfunction following COVID-19 infection: an early experience. Clinical Autonomic Research. 2021;31(3):385-394.
Open original source in a new tab - [7]
Goldstein DS. The possible association between COVID-19 and postural tachycardia syndrome. Heart Rhythm. 2021;18(4):508-509.
Open original source in a new tab - [8]
Miglis MG, Prieto T, Shaik R, et al. A case report of postural tachycardia syndrome after COVID-19. Clinical Autonomic Research. 2020;30(5):449-451.
Open original source in a new tab - [9]
Johansson M, Stahlberg M, Runold M, et al. Long-haul post-COVID-19 symptoms presenting as a variant of postural orthostatic tachycardia syndrome. JACC: Case Reports. 2021;3(4):573-580.
Open original source in a new tab - [10]
Kanjwal K, Jamal S, Kichloo A, Grubb BP. New-onset postural orthostatic tachycardia syndrome following coronavirus disease 2019 infection. Journal of Innovations in Cardiac Rhythm Management. 2020;11(11):4302-4304.
Open original source in a new tab - [11]
Ormiston CK, Swiatkiewicz I, Taub PR. Postural orthostatic tachycardia syndrome as a sequela of COVID-19. Heart Rhythm. 2022;19(11):1880-1889.
Open original source in a new tab - [12]
Wallukat G, Hohberger B, Wenzel K, et al. Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms. Journal of Translational Autoimmunity. 2021;4:100100.
Open original source in a new tab - [13]
Oaklander AL, Mills AJ, Kelley M, et al. Peripheral neuropathy evaluations of patients with prolonged Long COVID. Neurology: Neuroimmunology & Neuroinflammation. 2022;9(3):e1146.
Open original source in a new tab - [14]
Abrams RMC, Simpson DM, Navis A, et al. Small fiber neuropathy associated with SARS-CoV-2 infection. Muscle & Nerve. 2022;65(4):440-443.
Open original source in a new tab - [15]
Marques KC, Silva CC, Trindade SS, et al. Reduction of cardiac autonomic modulation and increased sympathetic activity by heart rate variability in patients with Long COVID. Frontiers in Cardiovascular Medicine. 2022;9:862001.
Open original source in a new tab - [16]
Asarcikli LD, Hayiroglu MI, Osken A, et al. Heart rate variability and cardiac autonomic functions in post-COVID period. Journal of Interventional Cardiac Electrophysiology. 2022;63(3):715-721.
Open original source in a new tab - [17]
Fu Q, Levine BD. Exercise and non-pharmacological treatment of POTS. Autonomic Neuroscience. 2018;215:20-27.
Open original source in a new tab - [18]
Raj SR, Black BK, Biaggioni I, et al. Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more. Circulation. 2009;120(9):725-734.
Open original source in a new tab - [19]
Taub PR, Zadourian A, Lo HC, et al. Randomized trial of ivabradine in patients with hyperadrenergic postural orthostatic tachycardia syndrome. Journal of the American College of Cardiology. 2021;77(7):861-871.
Open original source in a new tab - [20]
Sheldon RS, Grubb BP 2nd, Olshansky B, et al. 2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope. Heart Rhythm. 2015;12(6):e41-e63.
Open original source in a new tab - [21]
Vernino S, Bourne KM, Stiles LE, et al. Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1. Autonomic Neuroscience. 2021;235:102828.
Open original source in a new tab - [22]
Bryarly M, Phillips LT, Fu Q, et al. Postural orthostatic tachycardia syndrome: JACC Focus Seminar. Journal of the American College of Cardiology. 2019;73(10):1207-1228.
Open original source in a new tab - [23]
Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: major findings, mechanisms and recommendations. Nature Reviews Microbiology. 2023;21(3):133-146.
Open original source in a new tab - [24]
Al-Aly Z, Xie Y, Bowe B. High-dimensional characterization of post-acute sequelae of COVID-19. Nature. 2021;594(7862):259-264.
Open original source in a new tab - [25]
Xie Y, Xu E, Bowe B, Al-Aly Z. Long-term cardiovascular outcomes of COVID-19. Nature Medicine. 2022;28(3):583-590.
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Understanding includes the limits.
This is an AI-assisted evidence summary, not a clinician endorsement. Read each original paper for its complete methods, population and limitations. Different studies can ask different questions and report different kinds of results.
Dates marked “added” describe when a finding entered this monitor, not when the study was published or clinically reviewed. Personal health and treatment decisions belong in a conversation with a qualified clinician.