Study reading
Two active programs showed similar asthma-control improvements
Physically inactive adults with moderate-to-severe uncontrolled asthma were randomized to treadmill training or a behavioral program to increase daily activity. Both groups showed clinically meaningful improvements in asthma control and quality of life, maintained at four-month follow-up. Because two active programs were compared, these changes do not establish benefit over receiving no program. Because the trial compared only two active programs, improvement in both does not establish benefit over no program; similar results also do not prove the programs equivalent. The cohort was physically inactive and was predominantly women with several reported health characteristics, so the same results are not established for everyone with asthma. With 27 and 25 participants in the groups, these estimates remain uncertain and need confirmation in larger studies. The last reported assessment was after four-month follow-up, so outcomes beyond that point are not established.
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Physically inactive adults with moderate-to-severe uncontrolled asthma were randomized to treadmill training or a behavioral program to increase daily activity. Both groups showed clinically meaningful improvements in asthma control and quality of life, maintained at four-month follow-up. Because two active programs were compared, these changes do not establish benefit over receiving no program.
What the study found
Physically inactive adults with moderate-to-severe uncontrolled asthma were randomized to treadmill training or a behavioral program to increase daily activity. Both groups showed clinically meaningful improvements in asthma control and quality of life, maintained at four-month follow-up. Because two active programs were compared, these changes do not establish benefit over receiving no program. Source ↗
Both groups reached clinically meaningful improvements in asthma control and quality of life after the programs and at four-month follow-up. Source ↗
Who and what was studied
Participants were physically inactive adults with moderate-to-severe uncontrolled asthma; most were women, overweight or obese, and had anxiety and depression symptoms and low quality of life. Source ↗
The trial compared treadmill-based aerobic training with a behavioral intervention intended to increase daily physical activity. Source ↗
What remains uncertain
Because the trial compared only two active programs, improvement in both does not establish benefit over no program; similar results also do not prove the programs equivalent. The cohort was physically inactive and was predominantly women with several reported health characteristics, so the same results are not established for everyone with asthma. With 27 and 25 participants in the groups, these estimates remain uncertain and need confirmation in larger studies. The last reported assessment was after four-month follow-up, so outcomes beyond that point are not established. Source ↗
Follow the evidence.
Source links and automated passage checks do not establish clinical review.
Supporting passages: Two active programs showed similar asthma-control improvements
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Both interventions yield similar improvements in clinical control and most outcomes. These results suggest that the choice of intervention should be based on the patient's preferences and the intervention centre's capacity to provide care.
PMID 42240891 · abstract-5
Supporting passages: Physically inactive adults with moderate-to-severe uncontrolled asthma were randomized to treadmill training or a behavioral program to increase daily activity. Both groups showed clinically meaningful improvements in asthma control and quality of life, maintained at four-month follow-up. Because two active programs were compared, these changes do not establish benefit over receiving no program. Because the trial compared only two active programs, improvement in both does not establish benefit over no program; similar results also do not prove the programs equivalent. The cohort was physically inactive and was predominantly women with several reported health characteristics, so the same results are not established for everyone with asthma. With 27 and 25 participants in the groups, these estimates remain uncertain and need confirmation in larger studies. The last reported assessment was after four-month follow-up, so outcomes beyond that point are not established.
Aerobic training (AT) or behavioural interventions (BI) to increase physical activity in daily life (PADL) improve clinical control in people with asthma; however, comparisons between these interventions remain poorly known.
PMID 42240891 · abstract-1
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Supporting passages: Physically inactive adults with moderate-to-severe uncontrolled asthma were randomized to treadmill training or a behavioral program to increase daily activity. Both groups showed clinically meaningful improvements in asthma control and quality of life, maintained at four-month follow-up. Because two active programs were compared, these changes do not establish benefit over receiving no program.
Aerobic training (AT) or behavioural interventions (BI) to increase physical activity in daily life (PADL) improve clinical control in people with asthma; however, comparisons between these interventions remain poorly known.
PMID 42240891 · abstract-1
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Supporting passages: Physically inactive adults with moderate-to-severe uncontrolled asthma were randomized to treadmill training or a behavioral program to increase daily activity. Both groups showed clinically meaningful improvements in asthma control and quality of life, maintained at four-month follow-up. Because two active programs were compared, these changes do not establish benefit over receiving no program.
Aerobic training (AT) or behavioural interventions (BI) to increase physical activity in daily life (PADL) improve clinical control in people with asthma; however, comparisons between these interventions remain poorly known.
PMID 42240891 · abstract-1
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Supporting passages: Both groups reached clinically meaningful improvements in asthma control and quality of life after the programs and at four-month follow-up.
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Supporting passages: Participants were physically inactive adults with moderate-to-severe uncontrolled asthma; most were women, overweight or obese, and had anxiety and depression symptoms and low quality of life.
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Supporting passages: The trial compared treadmill-based aerobic training with a behavioral intervention intended to increase daily physical activity.
Aerobic training (AT) or behavioural interventions (BI) to increase physical activity in daily life (PADL) improve clinical control in people with asthma; however, comparisons between these interventions remain poorly known.
PMID 42240891 · abstract-1
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Supporting passages: Because the trial compared only two active programs, improvement in both does not establish benefit over no program; similar results also do not prove the programs equivalent. The cohort was physically inactive and was predominantly women with several reported health characteristics, so the same results are not established for everyone with asthma. With 27 and 25 participants in the groups, these estimates remain uncertain and need confirmation in larger studies. The last reported assessment was after four-month follow-up, so outcomes beyond that point are not established.
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
PMID 42240891 · abstract-3
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
PMID 42240891 · abstract-4
Both interventions yield similar improvements in clinical control and most outcomes. These results suggest that the choice of intervention should be based on the patient's preferences and the intervention centre's capacity to provide care.
PMID 42240891 · abstract-5